Ain't going to read through the entire thread, so apologies if what I sprout is already been said.
But simply, wall up. If you have accounts set to public, set to private and ghost the fuckers that are attacking you, more air and time spent on trying to douse or get your side of the story across, is more time they have to twist and curve whatever petty nonsense they're trying to spin you with. Better to drop dead weight before it pulls you down further with it. Have single strike rule, if you catch even the smallest whiff of someone treating you like shit, using you for their own means, again, ghost, drop and move on, they aren't worth time nor energy. Beyond that, there's not much else you can do.
If it's a case of someone manipulating pictures, screenshots and the likes, say someone trying to take you down with a false rape allegation, then find the section of the chat and dump it entirely to the public, show the accuser of being a using little cunt, this and instances like this are the exception to simply ghosting/not engaging with the hubbub, because it'll leave a nastier scar that you'll need to deal with, one way or another, this one is probably the quickest solutions.
Or there's always have your shit set to always private and not engage/put yourself at risk to start with, works well for me. Feck the rest of the world.