I will keep magazines with those in them separate from what is fired into the range for practice
This is fine and understandable, you don't want to always be shooting $$$ when you could shoot $, but run at least a few magazines of the expensive rounds through your gun, that way you know it works with your firearm. Firearms are weird in that some guns (even the same model!) can just be picky about certain ammunitions.
Anecdotally, I had an uncle who bought very expensive hollow-points for his 1911 (insert joke about Kimber QC), only to realize in a panic at about 1:00AM when somebody was banging on his windows that the hollow-points would not chamber properly in his pistol. Whoever it was ran off, and when he tried the hollow-points at the range the next day he found that even if he could get them to chamber, they wouldn't cycle reliably.
Secondly, keep in mind the further the gap in performance between your rounds, the further off your zero will be when you start shooting past 50 meters or so.
I hate to break it to you, but just about anything fired indoors will cause immediate damage to your hearing.
I have the same disdain towards people who claim shotguns are louder than rifles, that is not factual.
This is true in the same way that being shot will cause immediate damage to you. It lacks nuance. If I had to pick I'd rather be shot by a .22, not a .50.
There's a world of difference between ~140 decibels from a 10/22 and ~155 decibels from an AR-15 (18inch). One can leave you with pain and loss of higher frequencies, and the other can lead to actual permanent deafness and permanent tinnitus. Pistols actually end up worse than rifles in a lot of cases because the barrel is so much closer to your ears.
Powerleveling slightly, but I've had to fire a pistol indoors without hearing protection. I fired 3 shots and I have loss of higher frequencies along with major tinnitus, mainly in my right ear due to the positioning of the pistol. The loss in QoL is significant and I'm no longer able to enjoy quiet areas like I used to. The NFA is evil, everybody should be able to have suppressors.