I've started up Dread and while I'm still pretty early I think it's fucking awesome, I'm having a great time with it.
As much as I love pixel art 2D there's something to be said for seeing Samus as a detailed 3D model with close ups and other neat little effects like lights from her suit sometimes being reflected on the floor, they're really making the whole thing shine in 2.5D as opposed to feeling like a forced concession to modern day.
And Samus feels amazingly tight and fun to control and the robot chase sequences bring something fresh to this style of game.