It seemed more like a false equivalency thing to me. The Karen caricature conflates a woman using sex toys with a NEET fucking a body pillow, and the audience is supposed to agree with the artist in that only the former is a "normal behavior." I mean, yeah, owning a body pillow is a far cry from "normal behavior," but you're still getting off to it, so insisting that it's totally different from a woman shoving silicone up her cooch seems a little silly. Saying that they're similar in this aspect is not "gaslighting," much as the artist wants you to believe it is.
I think it's more an excuse to shit on toxic nerdbros more than anything, because I don't think anyone in the real world — as in, not a caricatured strawman — is actually arguing that these two things are equally socially acceptable. Especially not a "Karen," a term that this artist uses to mean "woman I disagree with." Pretty sure Karen wouldn't be vouching for NEETS humping pillows when she could easily spend that time treating her son's malignant tumor with essential oils.