A lot? There are certain things that I have issues with and I have means to fix them. I mean yes, obviously NV doesn't really NEED mods, but it has its fair issues. but I do think Fallout modding is best when focused on being vanilla. If your content is indistinguishable from vanilla, its an A+ mod in my book.
I'd also say that if you haven't played vanilla NV then you don't really "get" modding and cannot fully understand it. Its like Brutal Doom versus vanilla Doom. To certain point, you're not even playing NV anymore. It also doesn't help that more often than not mod count correlates to how insufferable someone is to interact with.