TL;DR and Sargon of Akkad - Their videos are very informative and they always bring up amazing points. I can't really say much about them other then I highly recommend them.
Blaire White - Okay, so "who is she" you ask. Well, she's a transgender woman who isn't a SJW. In fact, her videos are directly against them. I also just find her kinda funny. Not THE funniest person out there, but her sass is very charming. (I also recommend Shoe0nHead if you like Blaire's videos)
Joel of Vinesauce - I'm not sure if he should count, but goddamnit, I think he's funny enough. Besides all the dumb memes he has created, his commentary is very entertaining (I especially love it when talks about his dad)
JonTron - Do I really need to say anything? I love him for the same reason the others love him!
I Hate Everything - His videos are very funny and his voice is PERFECT for the tone of them! Nothing else I can say, really.
Ashens - Again, his voice is perfect for his videos. I generally really like the delivery of everything he says. It's just entertaining and oddly relaxing. He needs to lay off the blind bags/boxes though...
Cinema Snob - I like him as opposed to someone like Doug Walker. His humor, although probably not for everyone, just feels a lot more genuine. He more so snarks at movies rather than review them, but there's still a charm in that. He also finds the weirdest, most obscure shit out there (line Fun in Balloonland) which makes his videos more unique.
edit: No longer into JonTron and I haven't seen a Blaire, Sargon, or TL;DR video in a long time. Focusing on politics isn't healthy for me.