I honestly don't think anyone from the show is going to have their life change all that much (unless they learn something from the experience and decide to make changes). But I don't think any of them will get any sort of huge following online or anything.
Josie could probably get a nice little following if she decided to stream, but I am not sure she'd like the weird sexual attention from her fans. She might do it to make ends meet, but she's not gonna be like some huge star.
Letty could maybe milk some followers too, but it would be in her best interest to just get off the internet forever, because it's rotted her brain. Girl needs some normie hobbies with normie people, it would do her fucking wonders.
Vance will probably try to do some comedy shit but it won't get any traction. Occasionally he'll wake up in a cold sweat remembering how much he embarrassed himself in front of Sam and Frank, but otherwise his life won't change much. Hopefully he'll be inspired to give up on his comedy dreams and get a better job since he seems like someone who wants to have a normal life.
Can't see anything changing for Sylvia, girl doesn't even really have any simps. She'll probably just always be living the white trash barfly lifestyle.