You know, it just hit me, Im surprised that Sucker Punch isnt seeing the potential of bringing Infamous back in this age of capeshit, especially something takes a more realistic touch in it...tho I legit wouldnt want a Second Son sequel. I dont know why, I felt like S.S's story was decent as a stand alone spin off in the same universe, it never felt to me like a true sequel to the series.
So in that case we are kind of stuck between two options
1)Remake/Reboot
2)Sequel that brings Cole back to life
To 1, it is what you get, a remake/retelling of the events of the first game...after Spiderman PS4, I think we have the blueprint of something special in there. We could have a much more active, alive and interactive Empire City. One of my problems with the original is that Empire City was VERY much the same all over with the "closest" to a fast travel system being "surfing" on the train tracks. I would make E.C bigger and more active. Shit could get very repetitive too with the side missions so giving more variated ones would also help. We could also get some commentary on the Covid Pandemic (tho knowing how media is bias, we probably would get pretty much "anti mask people bad" or something simple like that). Either way, now that we are apparently remaking the PS3 era (god, Im old), Infamous should be on the list.
To 2, we might as well bring Cole back to life. One may be asking how would he be alive and why we didnt know he was alive until now. The answer is simple, Cole was never "truly" dead and rather stuck in a Superman like coma, bring brought back when a lightning bolt hit the ship he was in. Is it a bit cheap? Indeed but S.S already jumped the shark when the RLI didnt kill every Conduit on Earth and just "most of them", Im pretty sure we could make up some excuse saying Cole's electrical powers either protected him or adapted to the RLI energy so Cole wouldnt be 100% dead.
Now as to why we didnt learn of this until now, it was simple, Cole and Zeke both agreed it was best to lay low and pretend he is still dead for a while. I would imagine we could follow Cole's time as this underground anti-hero between the events of 2 and SS. The game just be this simple midquel to just bring us back to the series or it could end with maybe the confirmation that the bad ending of SS is canon and Delsin has gone mad with all the powers he has absorbed and Cole knows that he now represents a threat to everyone on the planet, almost The Beast dangerous so we could have Good Cole vs Evil Delsin at the end.
Cole: You got a lot of tricks, kid
Delsin: More than I can count!
Cole: And yet you didnt master any of them. I, on the other hand... *arms sparking with pure power* Quality vs Quantity....!
Tho to those who would prefer the good ending of SS to be canon, maybe the ending sets up some sort of major threat for the future and Cole recognises he needs more conduits on his side. The game ends with him ambushing a young man mid spray painting a wall in the middle of the night, the man turns around and its revealed its Good Delsin...Either way, we got the setup for more sequels.
Again, it kind of feels like this is the only way to move the series forward that would really bring veterans back and maybe even some of the SS fans as well with the setup Delsin and Cole will be working together against a new threat in the future that might make the beast look tame in comparison.
Edit: Forgot to mention that in this "sequel" of mine, Cole's powers are fused with the RFI, making him not only more powerful but also adding this "disabling" ability that could stop conduits without killing them, simply shutting their powers off temporarily (you could still kill them tho, maybe that would even be preferable in a pragmatic way). So in a way, if Evil Delson attempts to copy Cole's powers, it would backfire on him HARD as it could release fatal amounts of RFI energy within his body and killing him.