I'm sure Trey and Matt would absolutely lampoon Tony into oblivion if they knew about him. He's the exact kind of person the South Park boys are always criticizing; self-important, pompous, obnoxiously political, lazy, mooching, easily offended, suffering from Special Snowflake Syndrome, manchild...the list goes on and on.
Trey and Matt once said "We don't like Conservatives, but we fucking HATE Liberals." during an interview. And you can really tell. They rip the shit out of everyone and anyone, but they tend to really stick it to Leftists with a viciousness. The question is; if South Park were to rip into Tony, how obvious would they have to be for his dense ass to realize he's being made into a joke?