Lately the top three I would have to add to my list are Fallout New Vegas, Stalker SoC NS Joint Pak 2, and Doom 2016. I haven't actually finished F4 so I can't say much about that though.
For FNV it's because of my kleptomania. The stuff from the DLCs plus the stuff from mods makes almost everything have a use. Paperweights? Dubious Craftsman from More Perks lets me turn those into Gammorah chips. Bent tin cans? The Underground Hideout mod has an incinerator that can melt them down to scrap metal. Hell, World of Pain for Dead Money adds tons of new vendor codes for stuff like Scrap Metal and Electronics, more ammo types, flour, all vanilla nuka-cola variants, etc.
I'd say one of my favorite things, even if it IS a bit dumb to have be a perk, is from More Perks called Drink to Last. You can fill any bottle except milk bottles at a toilet and it becomes dirty water. But there's a water purifier in the Underground Hideout, so you can amass water much sooner than OWB.
I guess it's kind of like a race to me, to be honest. When I play, I always play in the mindset of "me, me, me". I want to just amass tons of supplies and ammo, organize it nice and neat in a little hideout away from civilization, so my guy basically has it made. So FNV does that for me with a few mods and the DLCs.
For NS Joint Pak 2, it's a crazy Russian mod for Stalker SoC, and it's super autistic, but I love it. It's basically a "everything and the kitchen sink" mod, where the balance is wonky, sometimes outright unfair unless you fully spoiler yourself and know what you're doing ahead of time, or rollback to an earlier save after realizing what you're up against next and prepare for it, but by the endgame it feels rewarding if you're smart with your ammo, supplies, weapons. You can amass a whole armory's worth of gear by the endgame and feel like the biggest badass in the Zone.
For Doom 2016 I legitimately deleted my profile and replayed the entire story maybe three or four times. I just love killing demons, and the singleplayer is strong. Sometimes I revisit it to chill and play that arcade mode where you replay levels for points once in a while.