PL'ing here but wtf.
He had Sertraline (zoloft), Remeron (mirtazipine), Anafranil, Escitalopram (lexapro), and that Guanfacine.
I've overdosed on Zoloft, I've overdosed on Remeron, I've overdosed on Lexapro.
But not at the same time. Just for kicks really. Like taken a whole strip (30 tablets) when you find out a few weeks later this shit doesn't work at all (it does for some people so don't take this as medical advice).
I also saved my buddy's life after him od'ing on Anafranil. But he also took a couple of strips and drank a six pack of tenents super and he was ok a couple of days later. Took him to emergency, waited all night for him to wake up. More the booze really.
I will say some of them make you feel shitty ill for a few days, and maybe I'm lucky I didn't get serotonin syndrome, but seeing as those things take days like 4-6 weeks to build up your serotonin, I don't think there's much chance of them doing it overnight. Might be wrong.
Some drugs are contra-indicated for causing SS, like any one of them with food supplements like Tryptophan or Tramadol with Remeron even. Having said that, I took a shit load (full strip) of both Tramadol and Remeron at once (over a nightly period) and I've never felt so fucking fabulous...
No idea about Guanfacine - that might be the one to push you over the edge.
Was that his stash? Did he take it all in one?
If I was going to hang myself, and I have thought about it, I would want to be lucid and on the fucking ball, because that is one trick you don't want to mess up. Near was a clever guy - pretty sure if he wanted out he would not use the double method of drugs to dull your senses.
As I understand it, hanging with drug od is not as common as drug od with alcohol od. Most people who hang themselves are lucid. You need shit set up and you need to be good to go. People who blow their brains out with a double-barelled shotgun might get all het up in the heat of the moment when they are drunk, but hanging, no, on the whole, it's mostly men that do it, and it's mostly very forethought out before hand.
Near's little threat was an empty threat in every regard.
I'm not saying if he necked all those pills that he wouldn't have had SS or his liver pack up a week or two later (same as with Paracetamol or Acetaminophen I think you call it in the states). A lot of those SSRI's are metabolized by liver and whatnot, but it's not the same thing really. Paracetamol is a very very safe drug, that is very very dirty in OD. It basically shreds your liver like a cheese grater. Don't fucking do it.
THIS IS A PSA:
DO NOT OVERDOSE ON PARACETAMOL OR ACETAMINOPHEN. It will take you a week or more to die and no one will be able to help you. You won't get put out of your misery unless you live in The Netherlands. And every single doctor/nurse/relative will be haunted by your screams until the day they die.
Then again, just like Near, maybe that is what you want.
One final thing. I took most of those drugs back to my chemist to be disposed of. I wasn't stupid enough to do the whole lot in one go.
And as for the Codeine. One of my faves and one I get enough of to kill me twice over every month. Another no go. Some people have natural tolerance via their inbuilt genetic enzymes. Same way some people can get drunk on a pint, I can take massive amounts of opiods, not because I'm strong, but because my body is built that way. I get drunk easy though.
The point is, you really really have to work out how all this affects you. And no one really can at the end of the day if this is novel to you. Pharmacokinetics and Pharmacodynamics are an absolute minefield that no one really understands except maybe the finest minds on planet earth, involved with ongoing research.
Near new this. Others have said this in this thread. I just backed it up a bit (take it with a grain of salt). No fucking way he would take pills and neck himself. One or the other.
All those pills were for show. All easily available. None of them very deadly. Probably not even in combination (don't try this at home).
Make of this what you will.