My thoughts so far:
I played on the hard difficulty setting. It honestly feels like the perfect one for me and I'm a little afraid to go to the Insane difficulty. While the enemies are a little bullet-spongy, they do go down quickly if you place your shots right and even the easier ones are capable of fucking your shit up if you aren't paying attention. Almost all of my deaths so far are my own fault.
There weren't any game-breaking bugs or crashes on my end. A few cases of texture pop-in and moments where the game stops me so it can load the area, but those are resolved pretty quickly. Keep in mind that I kept the game's default settings at Medium and had crowd density set to high, so I somewhat expected it.
I can't give my thoughts on the story because I got distracted at the beginning before you go to the ripperdoc for the first time (by the prompt to pay $21000). I thought it was going to be somewhat difficult and time-consuming to get, but I'm level six and somewhere in the $60000 range by the time I've stopped for the day. The equipment and items I find are usually enough for whatever tasks I have, so I have no real need to spend my cash. There was really only one time I've bought anything and it was for the medical stuff that restores your health.
One major gripe I have is that you can't see how much ammo you have unless you press ALT to go into the weapon screen. Not so bad on its own, but it can really bite you in the ass in the heat of the moment when you think you have much more ammo than you actually have.
In the Last Login gig, why the fuck do I get the cops on my ass for shooting the guy at the end? I read the mail, learned about his involvement, turned down his offer, and the guy fucking bolts. I tried killing him as soon as I told him to fuck off, before he had a chance to stand up, but nope. Somehow the police in the infamously brutal Night City are instantly aware if you commit any crimes against "civilians".
Speaking of which, the wanted system in this game is weird. The game really wants to punish you for going on a killing rampage, so much so that they can spawn JUST out of eye-sight, making it seem like they just teleported. However, if you hide inside of your apartment or another safe area (either before combat or during it, I don't remember), you'll be instantly in the clear.
The driving mechanics, at least on the car I started out with, are stiff. Although I got used to it, there were more than a few times where I accidentally ran someone over or crashed into something.
While it's definitely not the best game of all time, I've enjoyed myself more than I thought I would.