If those were attempted, ghoul and android could get a pass but that means trying to make a playstyle as one fit if you wanted to go beyond the superficial appearances. FEV mutant means you'd have not only have to revamp dialogue, it means you'd literally have to make the character a pariah in the Wasteland if they looked like the super mutants, considering that people would see an FEV mutant as something that should be killed.
Race thing considered, ghoul would mean they'd actually have to make your character face racism and such that would end up being half-assed (people call you things like zombie, radiation actually heals instead of hinder but that may just be it) and not well done.