Hhrm. I'll wait until Andromeda is out for a bit and user reviews are in. One of the saddest things about the way the trilogy ended is that it effectively destroyed the world that had been built up in the previous games. We'll see how Andromeda deals with that.
As for the new characters that have been announced... I kinda like how the asari looks. I don't think she looks forcefully ugly. More androgynous, which makes me think of ME1 where they really pushed the "asari have no gender!" thing.
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I just hope the company gets some descent writers, if you're gonna have movie-like RPGs, you should have a solid plot and good writing. That was sorely lacking in DA2 and ME3. DA:I had issues, but it felt a lot more cohesive than DA2.