Medical Advice Thread - Does this look infected?

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Not really a health problem or anything I'm too concerned about but it'd be nice to know why it happens.

Why do I get hangovers without drinking? Over the last year I've been waking up hungover without having any alcohol. It dissappears 30-60 minutes after I've woken up. There will be a mild headache (probably 1 or 2 out of ten in terms of pain), looking at light is uncomfortable, and when people talk to me it makes me irrationally angry because I have a hard time following what they are saying. It's like I'm thinking too slow and get confused and angry. Sometimes I don't remember people talking to me but later they'll be all angry at me and when I ask why they say something like "I tried to talk to you and you just looked at me, frowned, and told me to fuck off".

So why am I a light-sensitive angry goblin first thing in the morning? Is it a dehydration thing? Is it a caffeine withdrawal thing (i have about 5 coffees throughout the morning then nothing until the next morning and the first thing i do when i wake up is have a coffee)? Or is it that once you hit a certain age you just don't function first thing in the morning anymore?
How much water do you drink before bed and during the night?
 
I'm pretty sure it's dehydration. I stop drinking water an hour before bed because otherwise I'll have to keep getting up to pee. I'm also a very sweaty boy and sweat a lot at night.

So how do I stay hydrated without having to get up to pee all the time? IV fluids and catheter?
 
I'm pretty sure it's dehydration. I stop drinking water an hour before bed because otherwise I'll have to keep getting up to pee. I'm also a very sweaty boy and sweat a lot at night.

So how do I stay hydrated without having to get up to pee all the time? IV fluids and catheter?
Water + electrolytes maybe?
 
I am professionally diagnosing you with urethral sounding and mental retardation. That's why you pee your pants.
 
I'm pretty sure it's dehydration. I stop drinking water an hour before bed because otherwise I'll have to keep getting up to pee. I'm also a very sweaty boy and sweat a lot at night.

So how do I stay hydrated without having to get up to pee all the time? IV fluids and catheter?
If the room is dry, get a humidifier.

On the other hand, why are you sweating all night? Do something about that.
 
Does carrying one PI*S variant of Alpha-1 antitrypsin deficiency make you just a carrier? How likely is it that my dad has two copies? He has severe COPD.

alpha.png
 
Found a lump on one of my nads. Not really rock solid, kind of spongey but not 'this is your baby factory' spongey. Right on the front too.
I'm kind of freaking out, but it could be a lot of things, I heard.

Absolutely make an appointment with a urologist for prompt evaluation. If your insurance requires a referral, promptly contact your primary care doctor and make an appointment with them so you can acquire the necessary referral.

Does carrying one PI*S variant of Alpha-1 antitrypsin deficiency make you just a carrier? How likely is it that my dad has two copies? He has severe COPD.

View attachment 3897609

Well, to explain this in a satisfactory way we have to discuss alpha 1-antitrypsin and its variants. At the locus for AAT there are 3 common alleles. The expected allele that provides full function is PI*M. The less severe of the two most common variant alleles is PI*S. The other variant PI*Z is the more severe of the two variants. Your genotype, as a heterozygote, assuming they didn't make a mention of any other variants besides this, would be PI*MS. As a result you are indeed a carrier for the PI*S reduced functional variant. However, you are also directly impacted by having this genotype. Having the genotype PI*MS means that you express 80% of the expected level of AAT function. Fortunately, this is the least severe of the known AAT functional variants. As far as how you should approach this information, discussing it with your GP would be the best first step.

Regarding your father, unfortunately, despite knowing your genotype, we don't know which copy came from which parent, or even if the variant you have is actually a de novo mutation (meaning you are the first one to experience this particular mutation in your family). The only way to know for sure would be for your father to also get tested. However, given his health history, I would say that is a strong possibility that your father is a heterozygous as well, or possibly homozygous.

Unfortunately, as a result of symptomatic alpha 1-antitrypsin deficiency (AATD) being widely considered to be substantially underdiagnosed, possibly by at least an order of magnitude, the true odds of someone having two PI*S or two PI*Z alleles or the PI*SZ genotype is not known, and cannot be calculated with any reasonable certainty. Given his medical condition, and your heterozygous state being confirmed, I would absolutely have him genotyped. If he does have AATD, the treatment would be substantially different from the standard approach to idiopathic COPD.
 
How late in life is too late to fix posture issues? I have been sitting and slouching my whole life but recently got into the habit of keeping my shoulders back and hips under my shoulders. This helped a bit but when I catch my reflection from a distance my head seems to jut out horizontally from my clothing.

I can't post pictures for powerleveling reasons but Floatzel here provides a good example of what I'm talking about:
1669476576800.png
Thanks to my recent efforts, my lower back isn't as bad as this, but the head and shoulders look exactly how I do when walking. My head juts forward from my collar the same way.

I'm in my mid-30s. Is there any point trying to fix this?
 
How late in life is too late to fix posture issues? I have been sitting and slouching my whole life but recently got into the habit of keeping my shoulders back and hips under my shoulders. This helped a bit but when I catch my reflection from a distance my head seems to jut out horizontally from my clothing.

I can't post pictures for powerleveling reasons but Floatzel here provides a good example of what I'm talking about:
View attachment 3940347
Thanks to my recent efforts, my lower back isn't as bad as this, but the head and shoulders look exactly how I do when walking. My head juts forward from my collar the same way.

I'm in my mid-30s. Is there any point trying to fix this?
Assuming youre anatomically normal and its just from years of bad posture then yeah you can fix it. It will take time and you probably wont see results as fast as youd like to see them but if you keep trying then eventually youll fix it.

Neck strengthening exercises might help speed things a long. Every so often whenever you remember just put your hands behind your head and try to push against your hands using your neck muscles.

googling forward head posture physiotherapy might help you find more exercises that will help.

I've heard of people using strapping tape or ktape to help fix posture but ive never looked into it so i dont know how effective it is.
 
I have an offtopic quetion: I am writing a thread on Nutrition and would like to let someone proof read it. It's a big post and a bit complicated. It touches on metabolization of different sugars and oxydation of fatty acids. I want to see if there are any questions, stuff that isn't clear, shitty formatting and so on. I tried to write is as clear and simple as possible but I'd like to know if that's the case before posting it. It's my first thread.
 
I have an offtopic quetion: I am writing a thread on Nutrition and would like to let someone proof read it. It's a big post and a bit complicated. It touches on metabolization of different sugars and oxydation of fatty acids. I want to see if there are any questions, stuff that isn't clear, shitty formatting and so on. I tried to write is as clear and simple as possible but I'd like to know if that's the case before posting it. It's my first thread.
I'm not big on nutrition but I'm familiar enough with metabolism if no one else is willing.
 
How late in life is too late to fix posture issues? I have been sitting and slouching my whole life but recently got into the habit of keeping my shoulders back and hips under my shoulders. This helped a bit but when I catch my reflection from a distance my head seems to jut out horizontally from my clothing.

I can't post pictures for powerleveling reasons but Floatzel here provides a good example of what I'm talking about:
View attachment 3940347
Thanks to my recent efforts, my lower back isn't as bad as this, but the head and shoulders look exactly how I do when walking. My head juts forward from my collar the same way.

I'm in my mid-30s. Is there any point trying to fix this?

It's known as "Forward Head Posture" and it can be corrected with the proper exercises. This is assuming you don't have a cervical/thoracic deformity from all the slouching. If it actually has impacted your cervical/thoracic spinal curvature then correction is unlikely. This is a good resource:

 
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Anyone know how to slow down menstrual cycles? Is it a sign of a deficit or excess of something?

I have an offtopic quetion: I am writing a thread on Nutrition and would like to let someone proof read it. It's a big post and a bit complicated. It touches on metabolization of different sugars and oxydation of fatty acids. I want to see if there are any questions, stuff that isn't clear, shitty formatting and so on. I tried to write is as clear and simple as possible but I'd like to know if that's the case before posting it. It's my first thread.
You ever get the nutrition thread up?
 
Anyone know how to slow down menstrual cycles? Is it a sign of a deficit or excess of something?


You ever get the nutrition thread up?
I'm still working on it. I made a deep dive into the metabolic cycles and how one leads into the other. I went way to deep, so that takes a lot of time.
 
Anyone know how to slow down menstrual cycles? Is it a sign of a deficit or excess of something?

Slow down? That's a new one on me. The menstrual cycle is very tightly regulated by an interaction of the pituitary gland and the ovaries. In some people is can have some some unusual variability, which after a certain point it is considered a medical disorder. Most women typically complain of long cycles or missed cycles if they have menstrual irregularity. If it happens with regularity any more frequently than every 21 days, I'd definitely get that looked into because constant premature cycling would be a risk factor for anemia if nothing else, not to mention the life disruption that occurs if one has a more severe menstrual syndrome than most.

I'm still working on it. I made a deep dive into the metabolic cycles and how one leads into the other. I went way to deep, so that takes a lot of time.

Human metabolic pathways are indeed a deep dive:

View attachment Yepk20IXyppuST6erisGCPg716Vbe06_6GFkm_SXVeg.png

(I would have thumbnailed it, but it didn't give me that option)
 
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Human metabolic pathways are indeed a deep dive:

View attachment 4164468
The one I am making will naturally not be as expansive but I added explanations at each step. I am trying to limit it to the pathways I need for the thread, which is easier said then done. Doing the research takes so much time, but at least I really understand what I am writing down. I am sadly not able to fit in the valence bond formulas to visualize the reactions.

Btw. Everyone who wants to read a paper or needs a book, look them up on Sci-Hub or Libgen. Free download baby. Fuck you Elsevier and Springer.
 
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