Resident Evil 6, which completely removed the "resident evil" from itself
by adding features. I'm not sure how much this qualifies, but it feels like it should as an edge case.
Don't get me wrong, I find the game to be a extremely interesting as a third person shooter, it's a very fun Co-op game, it had some of the most complex and granular controls I've witnessed outside of the insanity that was some of the MGS titles (I'm thinking of 3 and 4 specifically), but everything about how the game was a good 3rd person shooter, in combination with the story and tone, made the game feel utterly unlike a survival game since the answer to almost every problem was "gun go boom".
You might argue 4 started this trend, and I'd tend to agree it
started it, but even 4 and 5 kept the tone and design more about the survival, the kind of gimpy controls, as well as fights with things either best avoided, or unkillable with "gun go boom" tactics. Even the Revelations titles tried to keep with the tone despite nearly perfecting the basically shooter controls for 2. Hell, 2 went even harder with a survival tone to try to disguise the competent third person shooter underneath especially with some of those sneaky instagib enemies.
6 is just an unabashed shooter and that is fine, but it really feels like it removed something after playing previous titles, the tone is just such a mess and everyone looks like they're on steroids. It just doesn't feel like a resident evil game.
Similar to that, going from Rainbow 6: 3 (Raven Shield, Athena Sword, Iron Wrath) to Rainbow 6: Vegas.
The easy argument is they are different games, and they are: Vegas is better described as Kill.Vegas or Gears of Vegas, but there's a very real argument that they just removed features from the game going from 3 to Vegas as well.
First of all, in 3 you could plan multiple teams with waypoints and orders in the most autistic planning mode I'm ever seen in a shooter (I haven't played the original SWAT games tho): in theory, you can set all the squads to clean up a mission from observer mode iirc...should you be so inclined. Gone from Vegas. Manual leaning? Gone, but replaced with cover mechanics, still, gone strictly speaking. Shitloads of weapons? Thinned significantly. Retarded amounts of weapon customization including bullet type autism? Gone. Gimpy mode when injured? Gone, by necessity since health got Call of Duty'd in Vegas, but still gone.
While on the topic of Tom Clancy games that removed features, it's also worth revisiting the original Ghost Recon and its expansions, which IIRC removed granular injury effects from the game by a patch, they didn't even bother waiting for a sequel.
So, for example if you got shot in the arm, your weapon accuracy would be shit but your movement wouldn't be hindered, get shot in the leg, movement hindered and noisier (this mattered) but accuracy not as bad as if an arm, and so on. After one of the later patches they changed to Rainbow 6: 3 style "get shot go gimpy in exactly the same way every time" mechanics which was a significant step down.